AYAME Blackburn is a character in the video game killer7. As an orphan, she is present at the Immigration Bureau where Curtis Blackburn attacks. After killing everyone in the building, Blackburn turns his gun on the girl, however her fate is not shown. It is later revealed that Curtis actually trained her in combat, dubbing her AYAME Blackburn in the process. AYAME inherits a variety of martial arts techniques from the assassin, coupling them with her own natural talents. An avid cosplayer, AYAME dresses in a Japanese schoolgirl uniform and hides her identity behind the mask of a typical anime face. Her young age, status as an orphan and the fact that she first appears in an amusement park all demonstrate the character's juvenile innocence.
AYAME is first encountered in ISZK Land during the first half of the "Encounter" chapter, where the Smith Syndicate catch sight of her several times, only to elicit a quick flight. The Smiths finally confront her in a parking lot, where she introduces herself as the "Chairman of the Educational Guidance Council," and defends a bus ostensibly filled with orphans Curtis is preparing for his organ trade. Here she runs around the perimeter sporadically firing two machine guns, her speed making it difficult to be chased, even by Con Smith. The Smiths best her however, and she flees the scene on the bus she had been protecting.
After locating and infiltrating the Blackburn Residence, the Smith Syndicate face AYAME again in one of the home's chambers. This time, she hides behind a series of shutters that open and close at random, only to suddenly appear in one of three shafts of light to open fire. AYAME is overwhelmed by the Smiths and dies in combat. Falling to the ground, AYAME's mask dislodges, revealing to the player her identity as the Immigration Bureau orphan, although the Smiths are unaware of the significance. AYAME Blackburn's birth name is not clarified, and Hand in killer7 refers to her as the "Girl at Immigration and Naturalization Service."
- Japanese – あやめ・ブラックバーン (Ayame Burakkubaan)
- AYAME is consistently referred to as "Akane" instead of "Ayame" in the game's files.