Let It Die will be the first Grasshopper Manufacture project to benefit from GungHo's acquisition of the company, which will result in more prominent online features in a Grasshopper game than ever before. This game is currently identified as a free-to-play PlayStation 4 exclusive.
Flower, Sun, and Rain was considered for a follow-up around 2009, when Suda admitted he would like to write protagonist Sumio Mondo into a future video game.
Director Akira Ueda planned to pursue a Contact sequel without the involvement of Grasshopper Manufacture in 2006. While a sequel has yet to be developed, Ueda confirmed he would like to work with Suda on a second installment.
A sequel to No More Heroes 2: Desperate Struggle has been planned since 2009, however "it won't happen soon" according to Suda. He later reiterated he was not interested in returning to the franchise before 2030.
Composer Akira Yamaoka admitted in 2012 that he was considering a sequel to Shadows of the DAMNED, feeling relatively certain that Grasshopper would have support from Electronic Arts.
Suda spoke to Polygon of hopes for a Lollipop Chainsaw sequel in 2012. This interview took place before the game's release however and Suda has offered few other words about a second installment, so it is unclear if Lollipop Chainsaw is still considered sequel-material.
Suda described Killer Is Dead as self-contained in 2013, however he is open to directing a sequel if there is "enough demand from fans all over the world."